Tapley returned a kickoff 94 yards for a touchdown and added a 19-yard scoring catch from Bryn Renner for the Tar Heels (4-2, 1-1 Atlantic Coast Conference). They won their third straight, rolled up 533 total yards and claimed their first home victory over the Hokies (3-3, 1-1) since 1938.
Blue had touchdown runs of 1 and 13 yards, and Renner finished 17 of 30 for 194 yards with a touchdown pass and a 4-yard scoring run.
Logan Thomas was 26 of 49 for 354 yards with a 13-yard touchdown run and two long touchdown passes. Demitri Knowles took a kickoff 93 yards for a TD for the Hokies, who are off to their worst start since opening 2-3-1 in 1992.
Bernard surpassed his previous best of 165 yards set last year against Duke, and nobody has rushed for more yards against a Frank Beamer-coached Virginia Tech team. Bernard also became the Tar Heels' first 200-yard rusher since Ronnie McGill rolled up 244 against Wake Forest in 2003.
Bernard had two rushes of at least 50 yards -- including his 62-yard touchdown on a fourth-and-1 on the first play of the second quarter that put the Tar Heels ahead to stay.
North Carolina began to pull away midway through the third quarter, going ahead 35-20 on the Renner-to-Tapley touchdown pass before Knowles took the ensuing kickoff back for a touchdown.
Virginia Tech went for two, trying to make it a one-score game, but Thomas' pass over the middle didn't have a chance, and the Tar Heels scored the next two times they touched the ball.
Casey Barth kicked field goals of 44 and 40 yards for North Carolina. Its 48 points were the most scored in the series by either team, and the Tar Heels gained at least 500 total yards for the third time under new coach Larry Fedora.
The Tar Heels entered outscoring their previous three opponents at Kenan Stadium by a combined 155-6 and hadn't allowed a touchdown at home all season. Thomas didn't need much time to end that streak, bursting through on a 13-yard keeper to make it 7-0 barely 2 minutes in.
Tapley then tied it -- and started the Tar Heels' scoring binge -- by taking the ensuing kickoff back for a touchdown. That was the first kick return for a score against Tech since 1993, the longest streak in the country.
Ohio State remained No. 1 in the AP Top 25 and tied a poll record Sunday despite lagging support from voters. Meanwhile, No. 2 TCU and No. 3 Baylor edged forward and No. 4 Michigan State slipped.
Texas cornerback Kris Boyd has apologized for retweeting a Texas A&M fan during halftime of Texas' 50-7 loss to TCU on Saturday.
The Big 12 on Sunday acknowledged an officiating mistake that incorrectly awarded Oklahoma State a first down Saturday and said the officials involved would be disciplined.
Georgia coach Mark Richt says he's sticking with Greyson Lambert, who was just 10-for-24 for 86 yards in a loss to Alabama, as the Bulldogs starting quarterback.
Will Grier threw four touchdown passes to four receivers -- all in the first half -- and No. 25 Florida downed third-ranked Mississippi 38-10 on Saturday night.
Leonard Fournette highlighted his SEC-record third straight 200-yard game with a 75-yard touchdown run, and No. 9 LSU overcame Eastern Michigan 44-22 on Saturday night.