Only Mathews, who was listed day-to-day with a neck injury, has thrown for more yards (548) in a game for the Big Red (3-2). Amrhein, a senior getting his first extended playing time, completed 33 of 56.
Eleven completions went to Luke Tasker for a school-record 280 yards and a touchdown. Tasker has 47 catches for 764 yards this season.
Completions of 41 and 45 yards to Tasker set up Cornell's first two fourth-quarter touchdowns for a 34-23 lead. Both drives ended with short runs by Silas Nacita, who rushed for four touchdowns.
Kyle Frazier completed 35 of 45 passes for 451 yards and four touchdowns and is now second in career passing yards for the Hawks (3-3) with 6,275.
Linebacker Myles Jack, who suffered a season-ending knee injury, said Thursday he decided to leave UCLA and enter the 2016 NFL draft because he wants to be compensated for his skills.
The tougher tests await down the road for No. 3 Baylor Bears, but coach Art Briles has seen enough of his Bears to know this is his best team.
A decision has been made that Randy Edsall will not be the football coach at Maryland next season, and discussions are taking place about how and when to separate, a source said Thursday night.
Florida State running back Mario Pender has been released from the hospital but could be given a medical redshirt if he cannot return to the field this season.
Tennessee chancellor Jimmy G. Cheek has issued a statement amid rumors that alleges coach Butch Jones fought and punched senior offensive lineman Mack Crowder during a fall practice session.
With the addition of a few tweaks, UConn football coach Bob Diaco is still planning to bring a rivalry trophy with him to Florida on Saturday when the Huskies play UCF.