The decisive drive went 80 yards in 11 plays and took 2:46 off the clock.
Erik Lora caught 11 passes for 128 yards for Eastern Illinois (4-3, 3-1 Ohio Valley). Garoppolo completed 26 of 51 passes for 220 yards with a pair of interceptions. Jake Walker rushed for 103 yards and a touchdown.
Washaun Ealey had a big day for Jacksonville State (3-3, 2-2), rushing for 149 yards and three TDs.
The Eastern Illinois defense came up with three interceptions of Jacksonville State's Marques Ivory.
South Carolina AD Ray Tanner is not "100 percent sure" Saturday's game vs. No. 7 LSU will be played at Williams-Brice Stadium because of devastating floods that hit the state.
UCLA junior linebacker Myles Jack has withdrawn from school and will enter the NFL draft, making the decision just weeks after suffering a season-ending knee injury.
The Oklahoma State Cowboys' defense has lost senior middle linebacker Ryan Simmons for the season because of a knee injury.
A judge has dismissed simple assault charges against Rutgers wide receiver Leonte Carroo after the woman he allegedly attacked after a football game said she didn't want to testify.
Colorado coach Mike MacIntyre said he was sorry for getting into a sideline altercation with an assistant coach during a 41-24 loss to Oregon over the weekend.
The Fresno County District Attorney's office has filed charges against Fresno State QB Zack Greenlee and a teammate after both were arrested last month during a house party near the campus.