The Knights (5-2, 3-0 Conference USA) forced three Memphis turnovers, including a fumble on the UCF 1-yard line in the first quarter.
Murray, starting for the first time since the season opener, had 23 carries and scored twice early. He followed a 1-yard run with an 83-yard romp that was the second-longest run from scrimmage in school history.
Bouye had another big play when he recovered a fumble and ran 79 yards for a 28-10 UCF lead.
The Tigers rushed for a season-high 240 yards behind a career-best 88 yards by Jan Steib.
Ohio State quarterback Cardale Jones is "doing fine" after he was released from the hospital Wednesday night after being treated for symptoms related to a migraine headache.
East Carolina receiver Trevon Brown will miss three games after being placed on probation for a violation of the school's student code of conduct.
Five Rutgers players were suspended Thursday after home-invasion and assault charges, another jolt to a program whose coach is embroiled in an ongoing academics-related probe.
Nebraska coach Mike Riley announced the suspensions Thursday of five players, including three key contributors, for the Cornhuskers' season opener Saturday against BYU.
The Florida Gators will start Treon Harris at quarterback in Saturday's opener vs. New Mexico State over redshirt freshman Will Grier, coach Jim McElwain said Tuesday.
Baylor University has hired a Philadelphia law firm to independently investigate the university's handling of sexual assault complaints, including one against defensive end Sam Ukwuachu.