The game was tied at 35 when West's 4-yard TD capped a 74-yard drive with 7:39 left in the third quarter.
Enders added a 40-yard romp with 2:32 remaining to seal the victory for the Tigers (4-4, 3-2 Colonial Athletic Association).
West rushed for 144 yards and Enders had 122 as the Tigers rolled up 321 yards on the ground. Enders was 16 of 28 for 269 passing yards, including a 78-yard TD to West to give Towson a 21-14 lead late in the first quarter.
For the Wildcats (6-3, 4-2), John Robertson also threw for four touchdowns on 17-of-23 passing for 216 yards and ran for a 5-yard score.
Villanova's Kevin Monangai added 103 yards rushing and caught two touchdown passes.
The Playoff Predictor sees eight teams still alive for the playoff. Which teams have the most to win or lose?
Feleipe' Franks, the No. 4 pocket passer in the ESPN 300 and No. 59 player overall, committed to Florida after breaking his verbal pledge to LSU amid the Tigers' coaching uncertainty.
After finishing 97th in the FBS in scoring and 75th in passing yardage, Minnesota has fired offensive coordinator Matt Limegrover and passing game coordinator Jim Zebrowski, the school announced.
Clay Helton passed the latest round of the USC head coaching survivor test by beating UCLA, but there are still some who would prefer a big-time name.
Here are some names to remember in the coaching search at Georgia.
Six days after his death from brain cancer, hundreds of people, including Michigan football players, attended a memorial service for the 5-year-old grandson of former coach Lloyd Carr on Sunday.
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