Pierre set the tone early for Dartmouth (5-3, 3-2 Ivy League), scoring the first two touchdowns of the game- runs of 1-yard and 9-yards- to put Dartmouth on top in the first quarter 14-0. Pierre finished with 154 yards on 26 carries.
After Williams' touchdown pass to Justin Foley for 2-yards gave Dartmouth a 21-0 advantage, Jeff Mathews answered for Cornell (4-4, 2-3) finding Grant Gellatly for the 19-yard touchdown to cut the lead to 21-7.
Williams answered with one second remaining in the first half, finding Michael Reilly for the 22-yard touchdown and a 28-7 lead at halftime.
On the Big Green's first possession of the third quarter, Williams ran it in from 35-yards out to give Dartmouth a 35-7.
Dartmouth's lead was never contested, improving its record against Cornell to 55-40-1.
Ohio State remained No. 1 in the AP Top 25 and tied a poll record Sunday despite lagging support from voters. Meanwhile, No. 2 TCU and No. 3 Baylor edged forward and No. 4 Michigan State slipped.
Will Grier threw four touchdown passes to four receivers -- all in the first half -- and No. 25 Florida downed third-ranked Mississippi 38-10 on Saturday night.
Leonard Fournette highlighted his SEC-record third straight 200-yard game with a 75-yard touchdown run, and No. 9 LSU overcame Eastern Michigan 44-22 on Saturday night.
An officiating error led to an Oklahoma State touchdown Saturday in the Cowboys' 36-34 win over Kansas State.
Texas A&M receiver Ricky Seals-Jones, who was ejected for targeting midway in the second quarter of Saturday's game, took to Twitter late in the game, retweeting a tweet that questioned the call.
As if things weren't going bad enough at Texas, the Longhorns appear to have players on Twitter during lopsided losses and jabs at their coach accidentally being sent from other nearby teams.