The score came at the end of a nine play, 80-yard drive. Skon completed 5 of 5 passes on the drive for 92 yards, including a pair of passes to Macari, who finished the day with seven grabs for 71 yards.
Skon was 19-of-29 passing in the game for 231 yards and the score.
Macari's touchdown put Georgetown (5-5, 2-2 Patriot League) up 10-0 following Matt MacZura's 20-yard field goal in the first quarter.
Bucknell's Sean Cobelli hit a 37-yard field goal in the fourth quarter, ending the Hoyas' shutout bid.
The Bison (2-8, 0-5) managed just 168 yards of offense and seven first downs to Georgetown's 22.
The win snapped a four-game losing streak in the series for Georgetwon.
Ohio State remained No. 1 in the AP Top 25 and tied a poll record Sunday despite lagging support from voters. Meanwhile, No. 2 TCU and No. 3 Baylor edged forward and No. 4 Michigan State slipped.
Texas cornerback Kris Boyd has apologized for retweeting a Texas A&M fan during halftime of Texas' 50-7 loss to TCU on Saturday.
The Big 12 on Sunday acknowledged an officiating mistake that incorrectly awarded Oklahoma State a first down Saturday and said the officials involved would be disciplined.
Georgia coach Mark Richt says he's sticking with Greyson Lambert, who was just 10-for-24 for 86 yards in a loss to Alabama, as the Bulldogs starting quarterback.
Will Grier threw four touchdown passes to four receivers -- all in the first half -- and No. 25 Florida downed third-ranked Mississippi 38-10 on Saturday night.
Leonard Fournette highlighted his SEC-record third straight 200-yard game with a 75-yard touchdown run, and No. 9 LSU overcame Eastern Michigan 44-22 on Saturday night.