Hedrick replaced Southwick in the fourth quarter, well after the game was decided. He led the Broncos (8-2, 5-1 Mountain West) on a 56-yard drive of more than 9 minutes, capping it off with a 4-yard touchdown run.
Boise State was looking to recover from a bitter home loss last week to San Diego State, an upset that thwarted the Broncos' hopes of reaching a BCS bowl game this year.
In Honolulu, Boise State made sure the game's outcome was rarely in doubt. The Broncos defense finished with six sacks, three fumble recoveries and two interceptions. The sacks pushed down Hawaii's rushing total to -14 for the game.
Hawaii (1-8, 0-6) had its best play on special teams, with Mike Edwards returning a kickoff 100 yards for a touchdown to tie the game at 7-7 in the first quarter.
Quarterback Sean Schroeder of Hawaii was benched midway through the third quarter. He finished with 100 yards and an interception, while taking four sacks.
A crowd generously announced at just over 24,000 -- including many orange shirt-wearing Broncos fans -- cheered loudest when Schroeder was pulled from the game with roughly six minutes left in the third quarter. His backup, sophomore Jeremy Higgins, went on to complete one more pass, with 154 yards and an interception.
Higgins led the Warriors on their only offensive scoring drive of the game, a 10-play, 72-yard drive resulting in a 1-yard touchdown run for John Lister.
Will Gregory, who picked Hawaii over Boise State because he wanted to play running back instead of defense, was ejected in the first quarter for throwing a punch at an opposing player after a kickoff.
Daryl Gross, who spent a decade as Syracuse's athletic director, will start as Division II Cal State-Los Angeles' AD in July.
Freshman DB Chad Clay didn't last long with the Georgia football team, as the Bulldogs dismissed him following a second arrest in the past four months.
Brenda Tracy, who allegedly was sexually assaulted by four men, including two Oregon State players, in 1998 spoke Wednesday to the Nebraska football team.
A man who claims he told Penn State football coach Joe Paterno in 1976 that he was sexually abused as a teen by Jerry Sandusky asked a judge Wednesday to protect his identity and limit questions.
FOX Sports' Bruce Feldman joins The Paul Finebaum Show to share his thoughts on the upcoming National Championship race.
Urban Meyer, Thad Matta and Ohio State athletic director Gene Smith were among the crowd at the parade for the Cleveland Cavliers on Wednesday.