Hedrick replaced Southwick in the fourth quarter, well after the game was decided. He led the Broncos (8-2, 5-1 Mountain West) on a 56-yard drive of more than 9 minutes, capping it off with a 4-yard touchdown run.
Boise State was looking to recover from a bitter home loss last week to San Diego State, an upset that thwarted the Broncos' hopes of reaching a BCS bowl game this year.
In Honolulu, Boise State made sure the game's outcome was rarely in doubt. The Broncos defense finished with six sacks, three fumble recoveries and two interceptions. The sacks pushed down Hawaii's rushing total to -14 for the game.
Hawaii (1-8, 0-6) had its best play on special teams, with Mike Edwards returning a kickoff 100 yards for a touchdown to tie the game at 7-7 in the first quarter.
Quarterback Sean Schroeder of Hawaii was benched midway through the third quarter. He finished with 100 yards and an interception, while taking four sacks.
A crowd generously announced at just over 24,000 -- including many orange shirt-wearing Broncos fans -- cheered loudest when Schroeder was pulled from the game with roughly six minutes left in the third quarter. His backup, sophomore Jeremy Higgins, went on to complete one more pass, with 154 yards and an interception.
Higgins led the Warriors on their only offensive scoring drive of the game, a 10-play, 72-yard drive resulting in a 1-yard touchdown run for John Lister.
Will Gregory, who picked Hawaii over Boise State because he wanted to play running back instead of defense, was ejected in the first quarter for throwing a punch at an opposing player after a kickoff.
Check out the final seconds of Duke's win over Virginia, with the Cavaliers' Malcolm Brogdon scoring a go-ahead layup, followed by Grayson Allen driving to the other end to score an off-balance bucket at the buzzer.
John Lattner, the 1953 Heisman Trophy winner who helped lead Notre Dame to a 9-0-1 record and a No. 2 ranking in Frank Leahy's final year as coach, has died. He was 83.
Jabbar Juluke, the former running backs coach at Louisiana Tech who spent just one month at Texas Tech, will assume the same role on Les Miles' staff at LSU.
Corey Robinson is returning for his senior year on the gridiron at Notre Dame while also assuming the responsibilities of student-body president.
Baylor will hire more counselors and provide additional training for faculty in an effort to improve the school's response to sexual assault incidents, school regents said Friday.
Answering questions about the hype around two young quarterbacks, whether Stanford will sooner or later fall back into mediocrity and more.