Hedrick replaced Southwick in the fourth quarter, well after the game was decided. He led the Broncos (8-2, 5-1 Mountain West) on a 56-yard drive of more than 9 minutes, capping it off with a 4-yard touchdown run.
Boise State was looking to recover from a bitter home loss last week to San Diego State, an upset that thwarted the Broncos' hopes of reaching a BCS bowl game this year.
In Honolulu, Boise State made sure the game's outcome was rarely in doubt. The Broncos defense finished with six sacks, three fumble recoveries and two interceptions. The sacks pushed down Hawaii's rushing total to -14 for the game.
Hawaii (1-8, 0-6) had its best play on special teams, with Mike Edwards returning a kickoff 100 yards for a touchdown to tie the game at 7-7 in the first quarter.
Quarterback Sean Schroeder of Hawaii was benched midway through the third quarter. He finished with 100 yards and an interception, while taking four sacks.
A crowd generously announced at just over 24,000 -- including many orange shirt-wearing Broncos fans -- cheered loudest when Schroeder was pulled from the game with roughly six minutes left in the third quarter. His backup, sophomore Jeremy Higgins, went on to complete one more pass, with 154 yards and an interception.
Higgins led the Warriors on their only offensive scoring drive of the game, a 10-play, 72-yard drive resulting in a 1-yard touchdown run for John Lister.
Will Gregory, who picked Hawaii over Boise State because he wanted to play running back instead of defense, was ejected in the first quarter for throwing a punch at an opposing player after a kickoff.
Florida State coach Jimbo Fisher hopes quarterback Sean Maguire is ready to go full speed by the middle of June.
Graduate transfer quarterback Davis Webb has officially joined California, giving the Golden Bears an experienced option to replace No. 1 overall NFL draft pick Jared Goff.
First-year football coach Dino Babers, hired by former Syracuse AD Mark Coyle, is on the committee that will search for Coyle's replacement.
Hugh Freeze has some major holes to fill on offense with the departures of Laremy Tunsil and Laquon Treadwell, but there is Chady Kelly and good depth.
After transferring in from Montana State, Dakota Prukop has a checklist he's working from as he prepares to compete for the Oregon job.
The destination for Week 6 of the Big 12 Ultimate Road Trip is unanimous, as all three conference reporters would head to the Red River Rivalry.