Hayes kicked off the scoring just over six minutes in, capping a 66-yard drive with a 7-yard TD run. The Tigers (3-8, 3-4) led 21-0 at the end of the first quarter after Karam threw TD passes of 30 and 25 yards to Keiwone Malone and Alan Cross, respectively.
Karam found Jesse Milleson for a 2-yard touchdown pass with 6:41 left in the second quarter for a 28-3 halftime lead. The quarterback finished 14-of-16 passing for 147 yards.
The Blazers managed just 26 yards on the ground and 213 total. Kennard Backman scored UAB's lone TD on a 4-yard pass from Austin Brown with 6:00 left. Memphis blocked the extra-point try and returned it for two points and the final 46-9 advantage.
Running back Devontae Booker had 124 combined yards and a touchdown and Utah spoiled Jim Harbaugh's Michigan coaching debut, beating the Wolverines 24-17 on Thursday night.
ESPN 300 running back Elijah Holyfield, the son of former heavyweight boxing champion Evander Holyfield, has decided to stay home and attend Georgia, he announced Friday.
Arizona star linebacker Scooby Wright will have an MRI after injuring his left knee in the first quarter of the Wildcats' season-opening 42-32 win over UTSA on Thursday night.
Miami reserve linebacker Al-Quadin Muhammad has been suspended for the season opener against Bethune-Cookman on Saturday for a violation of team rules, a source confirmed to ESPN.com
All-American defensive end Shawn Oakman and safety Orion Stewart have been suspended for Baylor's season opener Friday against SMU for a violation of team rules, a school spokesman told ESPN.com.
Trevone Boykin threw for 246 yards and a touchdown and ran for 92 yards and another score to help No. 2 TCU outlast Minnesota 23-17 on Thursday night.