Eastern Illinois (1-0) snapped a 19-19 tie when Taylor Duncan capped a 12-play 75-yard drive with a two-yard TD run with 7:36 left in the third quarter.
Duncan, who rushed for 94 yards on 20 carries, would cap the night with a 45-yard TD run with 4:40 left.
Eastern Illinois built a 19-13 lead at halftime as Garoppolo completed 15 of 24 passes for 246 yards and threw touchdown passes of 37 and four yards to Lora and a 62-yard strike to Keiondre Gober that snapped a 13-13 tie with 3:22 left in the first half.
Lora caught 10 passes for 87 yards.
San Diego State (0-1) got a 48-yard touchdown run from Colin Lockett in the first quarter.
Florida State coach Jimbo Fisher hopes quarterback Sean Maguire is ready to go full speed by the middle of June.
Graduate transfer quarterback Davis Webb has officially joined California, giving the Golden Bears an experienced option to replace No. 1 overall NFL draft pick Jared Goff.
First-year football coach Dino Babers, hired by former Syracuse AD Mark Coyle, is on the committee that will search for Coyle's replacement.
Hugh Freeze has some major holes to fill on offense with the departures of Laremy Tunsil and Laquon Treadwell, but there is Chady Kelly and good depth.
After transferring in from Montana State, Dakota Prukop has a checklist he's working from as he prepares to compete for the Oregon job.
The destination for Week 6 of the Big 12 Ultimate Road Trip is unanimous, as all three conference reporters would head to the Red River Rivalry.
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