Wiltz scored his three touchdowns in the first half as the Cowboys (2-0) opened a 37-14 lead. He finished with 115 yards on 12 carries.
Stroud threw both touchdown passes in the third quarter, 33 yards to Ernest Celestie and 12 yards to Dylan Long. Stroud was 21 of 30 for 251 yards, becoming the fifth quarterback in school history to exceed 5,000 career passing yards.
McNeese had 528 yards of offense while holding the Golden Lions (0-2) to 216 yards. Arkansas-Pine Bluff has been outscored 120-25 in two games.
The Golden Lions tied the game at 14 on a 2-yard run by Jeremiah Young in the opening minute of the second quarter. The Cowboys then ran off the next 44 points.
South Carolina AD Ray Tanner is not "100 percent sure" Saturday's game vs. No. 7 LSU will be played at Williams-Brice Stadium because of devastating floods that hit the state.
UCLA junior linebacker Myles Jack has withdrawn from school and will enter the NFL draft, making the decision just weeks after suffering a season-ending knee injury.
The Oklahoma State Cowboys' defense has lost senior middle linebacker Ryan Simmons for the season because of a knee injury.
A judge has dismissed simple assault charges against Rutgers wide receiver Leonte Carroo after the woman he allegedly attacked after a football game said she didn't want to testify.
Colorado coach Mike MacIntyre said he was sorry for getting into a sideline altercation with an assistant coach during a 41-24 loss to Oregon over the weekend.
The Fresno County District Attorney's office has filed charges against Fresno State QB Zack Greenlee and a teammate after both were arrested last month during a house party near the campus.