The win is Fordham's first over an FBS opponent since it reinstated its football program in 1970 and advances the Rams to 3-0 this season. Temple, meanwhile, is 0-3 for the first time since 2007. This is the Owls' 11th all-time loss to an FCS team.
Nebrich completed 23 of 36 attempts for 320 yards and two touchdowns. His final pass, the game-winner, was reviewed when Temple challenged that Ajala was an ineligible receiver after he went out of bounds.
The touchdown was upheld when the referees ruled that Ajala was forced out and legally re-entered the field.
Temple nearly rallied in the second half behind emergency quarterback Connor Reilly, who started Temple's first two games but injured his right knee in the fourth quarter last week.
Temple trailed 20-7 in the third quarter but Reilly led the offense to three touchdowns on his first three drives, twice giving Temple the lead in the second half.
But on his final play of the game, Reilly engaged in a prolonged scrambled before he was finally sacked. He finished the game 7-for-8 passing for 69 yards with two touchdowns, after appearing in relief of senior backup Clinton Granger and freshman P.J. Walker.
Reilly said after the game that his injury is officially a bone bruise and a sprained ACL.
For Fordham, Ajala finished as Nebrich's leading receiver, with seven receptions and 134 yards. Carlton Koonce amassed 194 total yards and a touchdown on 26 rushes and four receptions.
Temple linebacker Tyler Matakevich recorded a game-high 14 tackles. Matakevich has led Temple in tackles in 10 of the 11 games he's started, dating back to last season.
South Carolina has decided to give up Saturday's home game against No. 7 LSU because of devastating floods that have hit the state, moving the game to Baton Rouge.
West Virginia All-Big 12 safety Karl Joseph is out for the remainder of the season after injuring his knee during a non-contact drill in Tuesday's practice.
Rutgers has reinstated senior wide receiver Leonte Carroo a day after an assault charge against him was dropped.
Tennessee senior wide receiver Alton "Pig" Howard has been dismissed from the team for a violation of team rules, coach Butch Jones announced.
UCLA junior linebacker Myles Jack has withdrawn from school and will enter the NFL draft, making the decision just weeks after suffering a season-ending knee injury.
Police charged a former Michigan football player with three felonies Wednesday related to an accusation that he filmed part of a sexual encounter with a woman without her knowledge or consent.