The Hawkeyes (3-1) now enter Big Ten play with a three-game winning streak, their longest since 2010.
Martin-Manley scored on returns of 83 and 63 yards early in the second quarter as Iowa jumped out to a 38-3 halftime lead.
Lowery took back picks for 35 and 13-yard TDs for Iowa, which scored its most points since it had 62 against Northwestern in 2002.
Tyler Van Tubbergen had 114 yards passing for the Broncos (0-4).
Nike Men's Iowa Hawkeyes Black/Gold Team Issue Performance PoloShop
SVP analyzes Jim Harbaugh's vague tweet criticizing the SEC for whining about his satellite camps, and reminds us of the coach doing some whining of his own during the season.
Texas A&M's Noel Mazzone talks with SEC Network's Kayce Smith about his decision to join the Aggies as the new offensive coordinator.
Florida linebacker Jarrad Davis discusses why he decided to return to Gainesville for his senior year.
Auburn head coach Gus Malzahn discusses how the Tigers went after big playmakers over the past few years.
Former University of Houston security guard Derrick Dewayne Hicks was indicted on Wednesday for an assault following UH's win in the AAC title game last December, according to multiple reports.
Tony Kornheiser suggests the SEC is looking to ban the Michigan football team from spending spring break in Florida because they fear Jim Harbaugh.