The Hawkeyes (3-1) now enter Big Ten play with a three-game winning streak, their longest since 2010.
Martin-Manley scored on returns of 83 and 63 yards early in the second quarter as Iowa jumped out to a 38-3 halftime lead.
Lowery took back picks for 35 and 13-yard TDs for Iowa, which scored its most points since it had 62 against Northwestern in 2002.
Tyler Van Tubbergen had 114 yards passing for the Broncos (0-4).
Nike Men's Iowa Hawkeyes Black/Gold Team Issue Performance PoloShop
LSU has landed its second ESPN 300 QB in two weeks, as No. 38 prospect Lowell Narcisse -- a 6-foot-3, 224-pound player from Louisiana -- has pledged to the Tigers for their 2017 class.
Anu Solomon is written in as the Wildcats' starting quarterback, but it's in pencil because of injury questions and the rising play of Brandon Dawkins.
After LB Jaylon Smith's injury in the Fiesta Bowl, the only Buckeye to visit him on the field was RB Ezekiel Elliott. On draft day, Elliott joined Smith to welcome him to the Dallas Cowboys.
Ten years ago the Auburn Tigers had it rolling under Tommy Tuberville, who was in the midst of winning a handful of SEC West titles.
Here's the latest from the recruiting trail in the Big 12.
Definitely not inspired by any popular TV shows, we looked up the best moments a team came back from the dead.