In a game which featured five ties and seven lead changes, Fales completed 28 of 35 passes for 431 yards and three touchdowns.
Fales threw touchdown passes of 83- and 77-yards to Jarrod Lawson and Chandler Jones, respectively, in the second quarter and San Jose State (3-3, 2-1 Mountain West) piled up 608 yards of total offense.
Lawson finished with 104 yards receiving and a game-high 98 yards rushing, including an 18-yard touchdown run in the third quarter.
Tyler Winston added eight receptions for 151 yards and a score for the Spartans.
Garrett Grayson had 310 yards passing and three touchdowns for Colorado State (2-4, 0-1 Mountain West), but threw two second half interceptions which led to 10 SJSU points.
Florida State coach Jimbo Fisher hopes quarterback Sean Maguire is ready to go full speed by the middle of June.
Graduate transfer quarterback Davis Webb has officially joined California, giving the Golden Bears an experienced option to replace No. 1 overall NFL draft pick Jared Goff.
First-year football coach Dino Babers, hired by former Syracuse AD Mark Coyle, is on the committee that will search for Coyle's replacement.
Hugh Freeze has some major holes to fill on offense with the departures of Laremy Tunsil and Laquon Treadwell, but there is Chady Kelly and good depth.
After transferring in from Montana State, Dakota Prukop has a checklist he's working from as he prepares to compete for the Oregon job.
The destination for Week 6 of the Big 12 Ultimate Road Trip is unanimous, as all three conference reporters would head to the Red River Rivalry.