In a game which featured five ties and seven lead changes, Fales completed 28 of 35 passes for 431 yards and three touchdowns.
Fales threw touchdown passes of 83- and 77-yards to Jarrod Lawson and Chandler Jones, respectively, in the second quarter and San Jose State (3-3, 2-1 Mountain West) piled up 608 yards of total offense.
Lawson finished with 104 yards receiving and a game-high 98 yards rushing, including an 18-yard touchdown run in the third quarter.
Tyler Winston added eight receptions for 151 yards and a score for the Spartans.
Garrett Grayson had 310 yards passing and three touchdowns for Colorado State (2-4, 0-1 Mountain West), but threw two second half interceptions which led to 10 SJSU points.
Under Armour Youth Colorado State Rams #18 Green Replica Football JerseyPrice: $55.00 Shop
A UCLA football player was suspended indefinitely Friday after he was arrested on suspicion of rape.
The tougher tests await down the road for No. 3 Baylor Bears, but coach Art Briles has seen enough of his Bears to know this is his best team.
A decision has been made that Randy Edsall will not be the football coach at Maryland next season, and discussions are taking place about how and when to separate, a source said Thursday night.
Appalachian State's board of trustees has approved a five-year contract for third-year football coach Scott Satterfield, who guided the Mountaineers through the transition from FCS to FBS.
Florida State running back Mario Pender has been released from the hospital but could be given a medical redshirt if he cannot return to the field this season.
The University of Wisconsin agreed to a 10-year deal with Under Armour on Friday worth a total of $96 million in cash and the retail value of products received.