Dartmouth (3-3, 2-1 Ivy) amassed 325 yards rushing and 575 of total offense while holding Columbia to just 95 yards.
Jon Marc Carrier got the scoring started with a 2-yard touchdown run in the first quarter and a 17-yard scoring reception in the second. Pierre later ran for a 37-yard score and McNamara returned an interception 24 yards for a touchdown on the ensuing Columbia possession to put the Big Green up 28-0 at halftime.
McNamara also had a 50-yard interception return for a score in the fourth that followed a stretch of three straight Dartmouth touchdown drives.
Columbia (0-6, 0-3) has been outscored 243-45 this year and clinched its seventh straight losing season and its 39th in the past 42 years.