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PHILADELPHIA (AP) -- Playing with a broken right ankle that could sideline him the rest of the regular season, Donovan McNabb had the best passing game of his career.

Allen's Analysis

Question on the Eagles: With McNabb out for up to two months, what are their playoff chances? McNabb's injury casts a cloud over their playoff hopes. Unlike some other teams that have several star players, McNabb is the guy for the Eagles. He's not only their quarterback but also their spiritual leader, so it will be hard for them to compete on a high level without him -- and this is crunch time. It's unfortunate, but it's part of the game. Question on the Cardinals: Is Plummer the answer at QB or should they let him go in the offseason Jake can be productive, but he's inconsistent. He could be more productive, though, with a better unit around him. The only thing consistent about the Cardinals is that the organization and Jake have been inconsistent. I think the Cards should hire a good GM and allow him to evaluate personnel. If that means letting Plummer go, there are some capable QBs out there. Eric Allen played cornerback for 14 NFL seasons with the Eagles, Saints and Raiders.

McNabb, injured on the third play of the game, tied a career high with four touchdown passes, leading the Philadelphia Eagles to a 38-14 victory over the Arizona Cardinals on Sunday.

But his status for the final six games is in doubt.

Eagles coach Andy Reid said this type of injury typically keeps players out six-to-eight weeks. McNabb, who has never had a serious injury, insists he'll try to play against San Francisco next Monday night.

"In my mind, I'll be out there,'' said McNabb, a two-time Pro Bowl quarterback.

However, the Eagles medical staff was less optimistic.

"It's not something he can play with right now,'' said trainer Rick Burkholder. "We'll know more in the next 24-48 hours.''

Koy Detmer probably would start in McNabb's place.

Unable to scramble because of his injury -- diagnosed as a sprain during the game -- McNabb stayed in the pocket and threw TD passes of 2 yards to James Thrash, 3 yards to Dorsey Levens, 27 to Todd Pinkston and 9 to Duce Staley in the first half.

Though he limped noticeably the entire game, McNabb didn't miss a play until resting with 4:49 left. He finished 20-of-25 for 255 yards and one interception, but had no rushing attempts for the first time in 53 career starts, including playoffs. Strangely, the Cardinals rarely blitzed McNabb even though he was hobbled.

"He wasn't coming out,'' Reid said. "I tried. I knew he was hurt. We didn't know this, though. He showed a lot of guts.''

Jake Plummer threw two TD passes for Arizona (4-6), which has lost four straight.

The Eagles (7-3) played nothing like the team that was dismantled by Indianapolis 35-13 at Veterans Stadium last week. They got TDs on all three second-quarter possessions, scored the last 24 points and racked up 463 yards.

Staley had 136 yards rushing and added 82 more yards receiving on three catches.

"They had a quarterback that was gimpy, but their running game was working so well,'' Cardinals coach Dave McGinnis said.

McNabb went down after he was sacked by Adrian Wilson and LeVar Woods on a third-and-3. He clutched his right leg and stayed on the turf after losing the ball, but returned on Philadelphia's next series.

"I tried not to think about it,'' McNabb said. "When the game was going on, I just focused on what I needed to do to get the win.''

Asked why he didn't get X-rays at halftime, McNabb said: "I wouldn't let anybody touch it.''

Kyle Vanden Bosch recovered McNabb's fumble at the Eagles 43, and Plummer connected with Jason McAddley on a 12-yard TD pass to give the Cardinals a 7-0 lead.

After Brian Mitchell returned the kickoff 45 yards to Arizona's 43, it took the Eagles six plays to score their first touchdown in the opening quarter since Week 2 against Washington.

McNabb connected with Thrash for 28 yards to the Cardinals 4. One play later, McNabb found Thrash in the back of the end zone for a 2-yard pass that tied it.

The Eagles took the lead for good 21-14 on McNabb's 27-yard TD pass to Pinkston. Pinkston ran a straight fly pattern down the left sideline, caught the ball in stride over cornerback David Barrett at the 2 and tightroped the sideline into the end zone for just his second TD catch in seven games.

"Donovan is a strong player, he's a warrior,'' Staley said.

After the Cardinals went three-and-out, McNabb drove the Eagles 62 yards in 1:14, connecting with Staley on a 9-yard TD pass. Staley gained 45 yards on a screen pass to start the drive and finished it by catching McNabb's toss at the 1 and dragging three defenders into the end zone.

McNabb's 3-yard pass to Levens gave the Eagles a 14-7 lead early in the second quarter. A 28-yard screen pass to Staley put the ball at the Cardinals 6. On third-and-goal from the 3, McNabb shoveled a pass to Levens, who ran in untouched for the score.

Arizona tied it at 14 on a 2-yard pass from Plummer to Joel Makovicka. Wilson set up the score by intercepting a pass from McNabb and returning it 35 yards to the Eagles 2.

David Akers kicked a 34-yard field goal for a 31-14 lead early in the third quarter. Thrash scored on an end-around from the 4 to make it 38-14.

"We're not executing mentally, a lot of mental errors, a lot of turnovers,'' Plummer said. ``We're all frustrated and baffled.''

Game notes

Eagles LB Carlos Emmons missed his third straight game with a strained hamstring. Doug Brzezinski started at left guard for John Welbourn, out with a calf injury. ... Makovicka left the game at halftime because of a concussion. ... McAddley's TD catch was the first in his career. ... Thrash's TD reception was his first since Week 4 against Houston. He had one TD catch in each of the first four games. ... Eagles CB Bobby Taylor had two interceptions. ... Plummer was sacked four times. ... The Eagles had the ball for 36:15.