Final

Colts 27

(2-1, 1-0 away)

49ers 7

(1-2, 1-1 home)

Coverage: CBS

4:25 PM ET, September 22, 2013

Candlestick Park, San Francisco, CA 

1 2 3 4 T
IND 7 3 3 1427
SF 7 0 0 07

Top Performers

Passing: A. Luck (IND) - 159 YDS

Rushing: A. Bradshaw (IND) - 19 CAR, 95 YDS, 1 TD

Receiving: A. Boldin (SF) - 5 REC, 67 YDS

Niners lose at home for first time with Colin Kaepernick as starter

ESPN.com news services

SAN FRANCISCO -- Andrew Luck faked out the defense, ran untouched into the end zone for a 6-yard touchdown and emphatically threw down the ball with a little extra oomph.

Even he thought it might be a career-best spike.

"It was nice to score," he said matter-of-factly of the moment.

Jim Harbaugh's former quarterback sure outplayed his current one, and it wasn't even close.

Luck passed for 164 yards while facing his college coach for the first time, and the Indianapolis Colts defeated the San Francisco 49ers 27-7 on Sunday.

Trent Richardson scored a 1-yard touchdown on his first carry in his Colts debut after being acquired on Wednesday from the Browns. He was drafted two spots behind top-pick Luck last year.

Ahmad Bradshaw added a 1-yard TD run in the final minutes, and Adam Vinatieri kicked a pair of field goals.

Luck kept coming through again to give Indianapolis (2-1) more opportunities.

"I know he's grinning from ear to ear," Colts coach Chuck Pagano said. "I've never seen him smile the way he was smiling after this one."

This marked Colin Kaepernick's first home loss at Candlestick Park as a starter.

Frank Gore ran for 82 yards after going for 60 total in his first two games, but there were few bright spots for Kaepernick as San Francisco (1-2) struggled to establish a passing game with tight end Vernon Davis sidelined by a hamstring injury. The defense committed numerous costly penalties for the third straight week.

Luck completed his initial six passes and spoiled the home team's reunion day between coaches on both sides who know each other's tendencies dating to their days at Stanford.

The Colts sure appeared to be better prepared.

Luck sent third-year coach Harbaugh to consecutive losses for the first time. He was happier about the fact his two sisters who attend Stanford got to see him play.

"I wasn't caught up in, 'Oh my gosh, I'm going up against Coach Harbaugh, (Greg) Roman and (Vic) Fangio," Luck said. "I figured any time you play this sport, coaches and players come and go so much that you always end up going against someone that you played for or played with or had a good relationship with."

Before Sunday, Harbaugh was 7-0 following a defeat -- and Harbaugh faced criticism for playing and starting Aldon Smith two days after the linebacker was arrested and jailed on suspicion of driving under the influence and marijuana possession.

49ers CEO Jed York said after the game Smith would seek treatment and miss Thursday's game at St. Louis and perhaps be away from the team longer. Smith apologized to "everybody I let down" while acknowledging he has a problem and will fix it.

Kaepernick had been 4-0 on his home field since becoming a starter last November. This time, his 49ers were 10½-point favorites, but looked nothing like the better team in getting thoroughly outplayed.

He completed 2 of his 8 first-half passes and wound up just 13 for 27 for 150 yards with an interception and three sacks.

"There's no one thing, we just didn't execute this offense," Kaepernick said.

The 49ers had six penalties for 48 yards and didn't look much better than they did in their five-turnover, 29-3 loss at division rival Seattle last week.

Kendall Hunter ran for a 13-yard score late in the first quarter, but San Francisco has scored 10 total points the past two games.

Richardson carried 13 times for 35 yards, giving the Colts quite the 1-2 punch with Bradshaw's 19 rushes for 95 yards.

Luck took advantage of a pair of penalties by San Francisco to open Indianapolis' seven-play, 80-yard scoring drive over the opening 3:40 for a 7-0 lead.

On the Colts' first play from scrimmage, safety Donte Whitner received a 15-yard unnecessary roughness penalty when he led with his helmet on a hit against Bradshaw after a 3-yard catch. Tarell Brown was flagged for pass interference on the next play.

Another penalty on Brown, for holding, gave the Colts a first down at the 23 midway through the second quarter and set up Vinatieri's 43-yard field goal. He kicked a 41-yarder in the third quarter.

Brown was penalized yet again for pass interference midway through the fourth.

Luck kept drives going with clutch plays as the Colts won the third straight meeting with San Francisco.

On third-and-9 and throwing from near his end zone late in the third, Luck hit Reggie Wayne for a 25-yard gain in which Wayne broke through several tackle attempts.

All-Pro linebacker Patrick Willis went down on the play and was helped off the field moments later with a groin injury that sidelined him for the rest of the game.

Willis declined to speak to reporters after the game. Harbaugh said he did not know the extent of Willis' injury.

The Colts busted through San Francisco's defensive line, which lost nose tackle Ian Williams to a season-ending ankle injury last week.

"It's one of those games you look back on down the road and say, 'This was a signature win, maybe one that helped you to do great things, that helped you accomplish the program you built,' " Pagano said.

Game notes


49ers special teams standout Bubba Ventrone left after the first quarter with a concussion. ... San Francisco TE Vernon Davis' streak of 98 straight games played was snapped. ... The 49ers had their regular-season winning streak vs. AFC opponents end at five. ... Gore has 2,687 career yards receiving, moving into second place in franchise history for a RB behind Roger Craig (4,442).

Information from ESPN.com's Bill Williamson and The Associated Press was used in this report.

Copyright by STATS LLC and The Associated Press

SPONSORED HEADLINES

Team Stat Comparison

 
IND
SF
1st Downs2314
Passing 1st downs
98
Rushing 1st downs
96
1st downs from penalties
50
3rd down efficiency
5-123-12
4th down efficiency
0-01-1
Total Plays6753
Total Yards336254
Yards per play5.04.8
Total Drives1111
Passing152139
Comp-Att
17-2613-27
Yards per pass
5.64.6
Interceptions thrown
01
Sacks-Yards Lost
1-73-11
Rushing184115
Rushing Attempts
4023
Yards per rush
4.65.0
Red Zone (Made-Att)3-41-1
Penalties1-106-48
Turnovers02
Fumbles lost
01
Interceptions thrown
01
Defensive / Special Teams TDs00
Possession36:2523:35

Passing Leaders

INDC/ATTYDSAVGTDINTSACKS
Luck17/261596.1001-7
SFC/ATTYDSAVGTDINTSACKS
Kaepernick13/271505.6013-11

Rushing Leaders

INDCARYDSAVGTDLG
Bradshaw19955.0127
Richardson13352.717
SFCARYDSAVGTDLG
Gore11827.5022
Kaepernick7202.9014

Receiving Leaders

INDRECYDSAVGTDLG
Heyward-Bey55911.8019
Wayne45814.5025
SFRECYDSAVGTDLG
Boldin56713.4024
Celek13030.0030

Scoring Summary

FIRST QUARTERINDSF
indTD11:23Trent Richardson 1 Yard Run (Adam Vinatieri Kick is Good)
Drive info: 7 plays, 80 yds, 3:40
70
sfTD4:20Kendall Hunter 13 Yard Run (Phil Dawson Kick is Good)
Drive info: 9 plays, 91 yds, 4:34
77
SECOND QUARTERINDSF
indFG7:00Adam Vinatieri 43 Yard Field Goal is Good
Drive info: 8 plays, 30 yds, 4:48
107
THIRD QUARTERINDSF
indFG6:51Adam Vinatieri 41 Yard Field Goal is Good
Drive info: 10 plays, 52 yds, 5:08
137
FOURTH QUARTERINDSF
indTD4:27Andrew Luck 6 Yard Run (Adam Vinatieri Kick is Good)
Drive info: 11 plays, 80 yds, 7:01
207
indTD2:58Ahmad Bradshaw 1 Yard Run (Adam Vinatieri Kick is Good)
Drive info: 3 plays, 8 yds, 0:56
277

Research Notes

Colin Kaepernick had a Total QBR of 11.8 against the Colts Sunday, his lowest in any career start. After posting a Total QBR of 89.8 in Week 1, Kaepernick has struggled in the last two weeks, especially with his downfield passing. He was 2-of-13 (15.4 percent) on throws more than 10 yards downfield in the last two weeks, after completing 52.6 percent of such throws against the Packers to open the season.
  [+]
Colin Kaepernick was 1-for-6 on passes traveling more than 10 yards downfield Sunday, continuing his recent struggles on such throws. Last year, Kaepernick completed 55.6% of his passes that were longer than 10 yards, fifth-best in the NFL (min. 60 attempts). Vernon Davis missed Sunday's game with the same hamstring injury that bothered him in Week 2. Davis had three catches for 69 yards and a touchdown on passes deeper than 10 yards downfield in Week 1.
  [+]
The 49ers defense, once the most imposing in the NFL, has been one of the worst over its last nine games (including the postseason).
  [+]

ESPN Stats & Information